Management of aphthous-like ulcer induce by trauma in patient with thalassemia beta intermedia: a case report

Dahlia Riyanto(1), Bagoes Soebadi(2), Priyo Hadi(3), Desiana Radithia(4),

DOI: https://doi.org/10.20956/jcrdm.v2i1.110

(1) Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
(2) Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
(3) Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
(4) Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

Abstract

Objective: Thalasemia is an inherited blood diseases cause which abnormalities systemically and intraorally. This case report to discuss management of Aphthous-Like Ulcer in 24 year old man with Thalasemia β Intermedia and need blood transfusion every month. Ulcer occured 2 days before transfusion.

Methods: Based on history, clinical examination, hematologi and ferritin tests.

Results: The diagnosis was Aphthous Like ulcer induce by trauma. Patient was treated using anti-inflammatory mouthwash and recovery was achieved within 3 weeks follow-up. Conclusion: Management of oral manifestation in Thalasemia patient need multidiciplinary approach to obtain successful therapy.

Keywords

Aphthous-like ulcer, Oral ulcer, Thalassemia β-intermedia

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References

Rachmilewitz EA, Giardina PJ. How i treat thalassemia. Blood 2011;118: 3479-3488.

Wang YP, Yu-Fong Chang J, Wu YC, et al. Oral manifestations and blood profile inpatients with thalassemia trait. J Formos Med Assoc 2013;112: 761-765.

Riyanti E. Dental and oral management in beta major thalassemia in children. Padjadjaran J Dent 2017;20.

Rujito L, Sasongko TH. Genetic background of β thalassemia modifier: recent update. J Biomed Transl Res 2018;4: 12.

Ahmed D, Bukhari K, Zafar H, et al. Awareness for diagnosis, management and preventive options of thalassemia. Ulutas Med J 2018;4: 66.

Muhammad ADS, Mahmood HPDS. Β thalassemia; a case report of oral and maxillofacial manifestation from population of Karachi Pakistan. Prof Med J 2017;24: 352-356.

Salma AMA. Orodental considerations in thalassemia patients. J Hematol Blood Disord 2016;2.

Scully C, Hodgson T. Recurrent oral ulceration: aphthous-like ulcers in periodic syndromes. Oral Surgery, Oral Med Oral Pathol Oral Radiol Endodontology 2008;106: 845-852.

Taher A, Musallam KM, Cappellini MD. Thalassaemia intermedia: an update. Mediterr J Hematol Infect Dis 2009.

Chiang CP, Yu-Fong Chang J, et al. Recurrent aphthous stomatitis-stiology, serum autoantibodies, anemia, hematinic deficiencies, and management. J Formos Med Assoc 2018;1: 1-11.

Joseph BB, George S. Haemorrheologicals: a new approach in the treatment of recurrent aphthous ulcer. Int J Res Med Sci 2014;2: 1200.

Karimi M, Cohan N, Sanctis V-De. Thalassemia intermedia; folic acid and vitamin B12 supplementation . What we know and what is needed ? presentation on. Iran J Ped Hematol Oncol 2016;7: 57-62.

Won SC, Han DK, Seo JJ, et al. Efficacy and safety of deferiprone (Ferriprox), an oral iron-chelating agent, in pediatric patients. Korean J Hematol 2010;45: 58.

Ricerca BM, Di-Girolamo A, Rund D. Infections in thalassemia and hemoglobinopathies. Mediterr J Hematol Infect Dis 2009.

Pham TAV, Nguyen NTX. Efficacy of chlorine dioxide mouthwash in reducing oral malodor: A 2-week randomized, double-blind, crossover study. Clin Exp Dent Res 2018;4: 206-215.

Srivenkatasatya NRM, Wang HH, Alluri S, et al. Phosphate buffer-stabilized 0.1% chlorine dioxide oral rinse for managing medication-related osteonecrosis of the jaw. Am J Dent 2017;30: 350-352.

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DOI: https://doi.org/10.20956/jcrdm.v2i1.110

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