Management of recurrent aphthous ulceration with iron deficiency anemia : a case report

Yuskhaidir Yuskhaidir(1), Desiana Radithia(2), Diah S. Ernawati(3),

(1) Resident of Oral Medicine Specialistic Programme, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
(2) Lecturer of Oral Medicine Department, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
(3) Lecturer of Oral Medicine Department, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia


Objective: Recurrent aphthous Ulceration (RAU) is a common oral mucosal disease characterized by recurrence and painful ulcers in non-keratinized oral mucosa.. A teenage girl aged 18 years 7 months comes with complaints of a lot of ulcers in the oral cavity. The patient said that she had had ulcers since 3 years ago, had no history of allergies, and with a weight that dropped below normal according to BMI standards. From intra oral examination multiple ulcers appear on the labial mucosa, buccal mucosa, painful gingiva and atrophy on the tongue.

Methods : Patients undergo complete blood tests with Hb results of 10.8 g / dL (N: 11.7–15.3 g / dL), Eosinophils 5% (N: 2-4%), Neutrophils 42%, lymphocytes 42%, monocytes 8%, hematocrit 33%, MCV 68 fL, MCH 21 pg,  MCHC 31 g / dL.

Results : Based on history, clinical examination and laboratory examination, a diagnosis of recurrent aphthous ulceration related to iron deficiency anemia can be established with a differential diagnosis of minor type recurrent aphthous stomatitis. The results of the examination with a TIBC value of 437.1 H, Serum iron 48.61 L, and ferritin 62.71 L. Patients treated with non-steroidal anti-inflammatory mouthwash and multivitamins. Patients are instructed to increase intake of foods containing iron, fruits and vegetables and avoid fatigue or adequate rest.

Conclusions : Therapy RAU with a food-based approach and a drug-based approach chlorine dioxide, Iron Polymaltose Complex, folic acid and vitamin c


Key words : Recurrent aphthous ulceration, hemoglobin, iron deficiency anemia

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